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    Corrected Reticulocyte Percentage/Reticulocyte Production Index (RPI)

    Evaluates bone marrow response to anemia, often in sickle cell patients.

    INSTRUCTIONS

    This tool provides multiple calculations:

    • Absolute reticulocyte count: 
      • The number of reticulocytes in a volume of blood.
      • Use when a direct measure of red blood cell production is needed, such as in early treatment response or non-anemic conditions with altered RBC turnover.
    • Corrected reticulocyte percentage/reticulocyte index (RI): 
      • Adjusts the reticulocyte percentage to account for the degree of anemia.
      • Can be appropriate as a quick assessment of marrow response in mild to moderate anemia, where adjusting for maturation time may not be necessary.
    • Reticulocyte production index (RPI): 
      • Adjusts the reticulocyte index to account for the longer maturation time of reticulocytes released prematurely from the bone marrow.
      • Useful in moderate to severe anemia, where reticulocytes are often released early. 
    %
    × 10⁶ cells/µL
    %
    %

    Result:

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    Poorana Priya
    Poorana Priya
    About the creator

    Poorana Priya is a postgraduate pathologist practicing in India at Sree Balaji Medical College & Hospital.

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    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.