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    NAFLD (Non-Alcoholic Fatty Liver Disease) Activity Score

    Diagnoses steatohepatitis, based on histology, in NAFLD patients.

    INSTRUCTIONS
    • Use in patients who have had liver biopsy for NAFLD. The score should not be used as a surrogate for NASH diagnosis (see Brunt and Kleiner 2011 for details).
    • Note: NAFLD is now termed metabolic dysfunction-associated steatotic liver disease (MASLD), and nonalcoholic steatohepatitis (NASH) is called metabolic dysfunction-associated steatohepatitis (MASH).

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    Dr. David E. Kleiner
    Dr. David E. Kleiner
    About the creator

    David E. Kleiner, MD, PhD, is an anatomical pathologist at the National Cancer Institute. He is also director of clinical operations and chief of the postmortem pathology section at the NIH. Dr. Kleiner’s research focuses primarily on chronic liver disease and transplantation pathology.

    About the Creator
    Dr. David E. Kleiner
    Dr. David E. Kleiner
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