tPA Contraindications for Ischemic Stroke

INSTRUCTIONS

Institutions may have slightly different absolute and relative contraindications to Tissue Plasminogen Activator (tPA); this list is meant to be a quick reference, but practice should be guided by institutional protocol and consultation with neurology. Reflects recommendations from Demaerschalk et al, Stroke 2015.

Dr. Edward C. Jauch

About the creator

Edward C. Jauch, MD, MS, is a professor and director of emergency medicine at the Medical University of South Carolina. He was chair of Stroke Council for the American Heart Association/American Stroke Association and primary author for the new Acute Ischemic Stroke guidelines. Dr. Jauch conducts research in acute ischemic stroke care, biomarker development in cerebrovascular injuries and other neurologic emergencies.

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tPA Contraindications for Ischemic Stroke