PERC Rule for Pulmonary Embolism
Rules out PE if no criteria are present and pre-test probability is ≤15%.
0 criteria
If no criteria are positive and clinician’s pre-test probability is <15%, PERC Rule criteria are satisfied.
Dr. Kline's comments about the PERC Rule for MDCalc:
“I derived the PERC rule to give some objective backing to the situation where you have considered PE in the active differential diagnosis, but really do not think any diagnostic test is necessary. To capture that concept scientifically, I validated the PERC rule to exclude PE with a gestalt pretest probability of <15% for PE and all eight criteria of the PERC rule are negative.”
Jeffrey Kline, MD, is a professor of emergency medicine and physiology and the vice chair of research at Indiana University. Among other research, he has conducted clinical studies using breath-based methods to diagnose and assess the severity of PE. He co-founded BreathQuant Medical Systems Inc to advance practical applications of 16 patents for medical devices. Dr. Kline has published over 50 manuscripts in the area of PE.
- Benjamin Slovis, MD