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    McDonald Criteria for Multiple Sclerosis (2017 Revision)

    Diagnoses multiple sclerosis.

    INSTRUCTIONS

    Changes from the 2010 McDonald Criteria:

    1. Presence of CSF-specific oligoclonal bands may now substitute for dissemination in time (DIT) even if baseline MRI findings do not meet DIT criteria.

    2. In patients with brainstem or spinal cord attacks, symptomatic lesions may now be included as MRI evidence of dissemination in space (DIS) or DIT.

    3. Cortical lesions may now fulfill MRI criteria for DIS (in addition to juxtacortical lesions).

    Clinical attacks
    Must have ≥1 clinical attack
    Lesions
    Must have ≥1 lesion

    Diagnostic Result

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    Dr. Alan J. Thompson
    Dr. Alan J. Thompson
    About the creator

    Alan J. Thompson, MD, FMedSci, FRCP, FRCPI, is the dean of the Faculty of Brain Sciences and the Garfield Weston Professor of Clinical Neurology and Neurorehabilitation at the University College London in London, England. He is also a senior investigator and faculty member at the National Institute for Health Research. Dr. Thompson’s primary research is focused on predicting outcomes in multiple sclerosis using MRI techniques.

    Are you Dr. Alan J. Thompson? Send us a message to review your photo and bio, and find out how to submit Creator Insights!
    MDCalc loves calculator creators – researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients.