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    Rome IV Diagnostic Criteria for Cannabinoid Hyperemesis Syndrome (CHS)

    Official Rome IV criteria for the diagnosis of cannabinoid hyperemesis syndrome.

    INSTRUCTIONS

    Use in patients with symptoms suggestive of cannabinoid hyperemesis syndrome (CHS) such as stereotypical episodes of vomiting, resembling cyclic vomiting syndrome (CVS), for at least the past 6 months, in the setting of prolonged cannabis use.

    Patients with any of the following features must be evaluated clinically for other diagnoses even though CHS may be present:

    • Signs or symptoms of GI bleeding.

    • Unexplained iron deficiency anemia.

    • Unintentional weight loss.

    • Palpable abdominal mass or lymphadenopathy on exam.

    • Family history of GI cancer and no recent upper endoscopy.

    • Dysphagia.

    • Persistent vomiting.

    • Neurologic symptoms.

    Must have the following:
    For 3 months prior with symptom onset ≥6 months ago
    Diagnostic Result

    Negative

    Diagnosis for cannabinoid hyperemesis syndrome as per Rome IV criteria
    Copy Results
    Dr. Douglas Drossman
    Dr. Douglas Drossman
    About the creator

    Douglas Drossman, MD, is professor emeritus of medicine and psychiatry at the University of North Carolina School of Medicine. He is founder, President Emeritus and Chief of Operations of the Rome Foundation. He is also the founder of the Drossman Center for the Education and Practice of Biopsychosocial Care and Drossman Consulting, LLC. Dr. Drossman has written over 500 articles and book chapters, has published two books, a GI procedure manual and a textbook of functional GI disorders (Rome I-IV), and serves on six editorial and advisory boards.

    Dr. Lin Chang
    Dr. Lin Chang
    About the creator

    Lin Chang, MD is responsible for the oversight and coordination of the Rome IV calculators on MDCalc. She is a Professor of Medicine at the Vatche and Tamar Manoukian Division of Digestive Diseases at UCLA and is a member of the Rome Foundation Board of Directors.

    The Rome Foundation
    The Rome Foundation
    About the creator

    The Rome Foundation is an independent not for profit 501(c) 3 organization that provides support for activities designed to create scientific data and educational information to assist in the diagnosis and treatment of Disorders of Gut-Brain Interaction (DGBI), also known as functional gastrointestinal (GI) disorders. Their mission is to improve the lives of people with DGBI. Over the last 3 decades, the Rome organization has sought to legitimize and update our knowledge of the DGBIs. This has been accomplished by bringing together scientists and clinicians from around the world to classify and critically appraise the science of GI function and dysfunction. This knowledge permits clinical scientists to make recommendations for diagnosis and treatment that can be applied in research and clinical practice. Diagnosis is based on the use of symptom-based criteria which are used in clinical trials and daily practice. The list of Rome IV categories and the Chair and Co-Chair of each chapter committee are listed below.

    Committees Chair Co-Chair
    Esophageal Disorders Ronnie Fass, MD John Pandolfino, MD
    Gastroduodenal Disorders Nicholas J. Talley, MD, PhD, FRACP Vincenzo Stanghellini, MD
    Bowel Disorders Fermin Mearin, MD Brian Lacy, MD, PhD
    Gallbladder and Sphincter of Oddi Disorders Grace Elta, MD Peter Cotton, MD
    Centrally Mediated Disorders of Gastrointestinal Pain Peter J. Whorwell, MD Laurie Keefer, PhD
    Anorectal Disorders Adil E. Bharucha, MD, MBBS Satish S. C. Rao, MD, PhD, FRCP
    Childhood Functional Gastrointestinal Disorders: Neonate/Toddler Sam Nurko, MD Marc A. Benninga, MD
    Childhood Functional Gastrointestinal Disorders: Child/Adolescent Carlo Di Lorenzo, MD Jeffrey S. Hyams, MD

    Rome IV Diagnostic Criteria Chapters, Chairs and Co-Chairs

    Rome IV Editorial Board: Douglas A. Drossman, MD, Senior Editor, Lin Chang, MD, William D. Chey, MD, John Kellow, MD, Jan Tack, MD, PhD, and William E. Whitehead, PhD.

    Content Contributors
    • David Cangemi, MD
    About the Creator
    Dr. Douglas Drossman
    Dr. Douglas Drossman
    Dr. Lin Chang
    Dr. Lin Chang
    The Rome Foundation
    The Rome Foundation
    Content Contributors
    • David Cangemi, MD
    Reviewed By
    • William D. Chey, MD, AGAF, FACG, FACP